Journal of Neurointensive Care

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Review Article

April 30, 2026

Evolution of the Monro-Kellie Doctrine from Static Intracranial Pressure to Dynamic Intracranial Physiology: A Critical Review of the Monro-Kellie 1.0 Through 4.0 Framework and Its Implications for Contemporary Neurocritical Care

Hyunchul Jung, Jae-Hyun Kim, Ga Young Park, Moinay Kim, Seungjoo Lee

J Neurointensive Care. 2026;9(1):1-10.

The Monro-Kellie doctrine, first articulated in 1783, established that intracranial volume remains constant within the rigid cranium. However, this static three-compartment model has proven inadequate to explain the full complexity...

Review Article

April 30, 2026

Shock Index as a Predictor of Mortality in Trauma: A Systematic Review and Meta-Analysis of Observational Studies

Ezequiel Garcia-Ballestas, Javier Villafane, Claudio Rivas-Palacios, Wendy Henriquez, William A Florez Perdomo, Miguel A Duran López, Tariq Janjua, Luis Rafael Moscote-Salazar, Amit Agrawal

J Neurointensive Care. 2026;9(1):11-18.

The shock index (SI) is a rapid and practical physiological parameter used to identify decompensated shock and assess severity in cases of progressive hemodynamic decline. This study aims to determine...

Review Article

April 30, 2026

Anaphylaxis to Mannitol: A Rare but Serious Threat in Neurocritical Care

Luis Rafael Moscote-Salazar, Tariq Janjua, Pratiksha Baliga, William A. Florez-Perdomo, Amit Agrawal

J Neurointensive Care. 2026;9(1):19-25.

Mannitol, an osmotically active and commonly employed agent in neurocritical care which is well tolerated. However, isolated case reports of IgE-mediated anaphylaxis impose a potential immunological risk, pertaining to CCD-sensitized...

Review Article

April 30, 2026

Pontine Hemorrhage Simulating Acute Coronary Syndrome

Pratiksha Baliga, Huber Said Padilla Zambrano, Yancarlo Ramos-Villegas, Daniela Lopez-Cepeda, Loraine Quintana-Pajaro, Tariq Janjua, Luis Rafael Moscote-Salazar

J Neurointensive Care. 2026;9(1):26-33.

Intracerebral hemorrhage in the pons can, on rare occasions, present with acute coronary syndrome-like symptoms via neurogenic cardiac findings, such as electrocardiographic changes and increased cardiac biomarkers. The challenge in...

Current Issue: Volume 9(1); Apr 2026

Cover Story

Editorial Office: Department of Neurosurgery, Korea University College of Medicine
73, Inchon-ro, Seongbuk-gu, Seoul 02841, Korea
Tel: +82-2-920-6833 Fax: +82-2-929-0629 E-mail: editor@e-jnic.org

Copyright © 2026 by Korean Neurointensive Care Society.

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